No, most vaccinated pregnant women in NZ haven't miscarried

AAP FactCheck November 05, 2021
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There are numerous global studies which support COVID-19 vaccination in pregnancy. Image by AP

As Australia and New Zealand push for high vaccination rates to combat outbreaks of the COVID Delta variant, attention has turned to vaccine hesitancy1 among pregnant women.

Tapping into the topic is a meme2 claiming that in New Zealand there had been 124 miscarriages among 180 pregnant women who had their first dose of COVID-19 vaccines - which it said was an 80 per cent death rate.

But the claim is baseless, with official figures showing 13 miscarriages had been recorded at the time of writing as potential adverse reactions in New Zealand during the COVID-19 vaccine rollout. These miscarriages were not necessarily linked to the vaccines, and multiple experts and studies say there is no evidence of an increased risk of miscarriage following vaccinations.

The meme - which incorrectly identifies 124 deaths as being 80 per cent of 180 when it is 69 per cent - does not provide a verifiable source for its data. However, a purported 80 per cent miscarriage rate following COVID-19 vaccination has previously been traced3 to blog posts that misinterpreted data in a preliminary study4 published in the New England Journal of Medicine. The figure has been debunked widely (see here5, here6, here7 and here8).

NZ data from Medsafe9 show there had been 13 miscarriages/aborted pregnancies reported as adverse events between the start of the vaccine rollout in February and October 16 (see adverse events of special interest).

Medsafe notes that while these and other reported adverse events may have occurred following vaccination they did not necessarily occur as a result of the vaccines. According to the NZ Ministry of Health website10, around 1 or 2 in every 10 pregnant women miscarry, while approximately 1 in every 200 pregnancies end in stillbirth.

The only COVID vaccine available in NZ is the Pfizer-BioNTech mRNA vaccine11. Major international health agencies such as the US Centers for Disease Control and Prevention12 advise pregnant women to get vaccinated as they are more likely to get severely ill with COVID-19 than the general population, while also pointing to studies that show there is no increased risk of miscarriage following receipt of an mRNA vaccine.

In June13, the Royal Australian and New Zealand College of Obstetricians and Gynaecologists and the Australian Technical Advisory Group on Immunisation issued a joint statement saying: "Global surveillance data from large numbers of pregnant women have not identified any significant safety concerns with mRNA COVID-19 vaccines given at any stage of pregnancy."

In New Zealand, the Ministry of Health14 provides similar advice. Juliet Rumball-Smith15, the ministry's clinical chief advisor, told AAP FactCheck in an email: "Data from millions of pregnant people who have already been vaccinated globally indicates that there are no additional safety concerns with administering COVID-19 vaccines at any stage of pregnancy."

Dr Rumball-Smith said research also showed "if you're not vaccinated and you are pregnant and catch COVID-19 you are more likely to be admitted to a hospital's intensive care unit and your baby is more likely to suffer harm".

Mary Nowlan16, a medical writer at the Immunisation Advisory Centre at the University of Auckland, told AAP FactCheck there was an increasing amount of literature supporting vaccination in pregnancy.

"Pregnant people need to be alerted to potential response to the vaccine (fever, muscle aches etc) and to monitor symptoms if they persist, but there is no evidence that these responses are likely to trigger miscarriages or increase risk for pregnancy complications," she said in an email.

"The risk from COVID-19 infection is much higher and life-threatening, especially late in pregnancy and postpartum, and in women with other health conditions such as diabetes, hypertension and obesity."

Dr Nowlan pointed to a review of studies17 showing no evidence of an increased risk of "spontaneous abortions" in pregnancy after vaccination with mRNA COVID vaccines.

A Norwegian study18 found no increased risk of first-trimester miscarriage following vaccination, while a US preprint study19 of smart-phone based surveillance data (v-Safe) also showed no increase in risk of spontaneous abortion following mRNA COVID-19 vaccines for preconception or in early pregnancy (prior to 20 weeks' gestation).

A British study20 showed there were no significant differences in perinatal outcomes between women vaccinated in pregnancy (140 women) or unvaccinated (1188 women).

Michelle Wise21, a senior lecturer in the Department of Obstetrics and Gynaecology at the University of Auckland, told AAP FactCheck that studies published this year comparing the outcomes for vaccinated pregnant women and unvaccinated women were consistent in their conclusions.

"The miscarriage rate is not different, nor is the rate of babies being born with abnormalities following exposure to the vaccine during the first trimester," she said.

"Moreover, all the pregnancy outcomes such as preeclampsia22, gestational diabetes, fetal growth restriction and preterm birth are the same - this is best shown by the BORN database23 where every pregnant woman in Ontario, Canada, is followed up."

False – The claim is inaccurate.

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Sources

  1. https://edition.cnn.com/2021/10/13/world/coronavirus-newsletter-intl-13-10-21/index.html
  2. https://archive.ph/g3i0R
  3. https://www.reuters.com/article/factcheck-vaccine-pregnancy-idUSL1N2OX1WL
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117969/#r15
  5. https://www.reuters.com/article/factcheck-miscarriage-vaccine-idUSL2N2NZ1UW
  6. https://www.politifact.com/factchecks/2021/aug/24/facebook-posts/claim-about-covid-19-vaccines-and-miscarriages-bas/
  7. https://fullfact.org/health/miscarriage-vaccine-misinfo/
  8. https://www.bbc.com/news/health-57552527
  9. https://www.medsafe.govt.nz/COVID-19/safety-report-33.asp
  10. https://www.health.govt.nz/your-health/pregnancy-and-kids/services-and-support-during-pregnancy/miscarriage-and-stillbirth
  11. https://covid19.govt.nz/covid-19-vaccines/get-the-facts-about-covid-19-vaccination/what-you-need-to-know-about-the-pfizer-vaccine/
  12. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/recommendations/pregnancy.html
  13. https://www.health.gov.au/news/joint-statement-between-ranzcog-and-atagi-about-covid-19-vaccination-for-pregnant-women
  14. https://www.health.govt.nz/our-work/diseases-and-conditions/covid-19-novel-coronavirus/covid-19-vaccines/covid-19-vaccine-health-advice/covid-19-vaccine-pregnancy-and-breastfeeding
  15. https://www.health.govt.nz/news-media/media-releases/clinical-chief-advisor-primary-health-care
  16. https://covid.immune.org.nz/node/477
  17. https://doi.org/10.3390/vaccines9090970
  18. https://www.nejm.org/doi/full/10.1056/NEJMc2114466
  19. https://www.researchsquare.com/article/rs-798175/v1
  20. https://pubmed.ncbi.nlm.nih.gov/34389291/
  21. https://unidirectory.auckland.ac.nz/profile/m-wise
  22. https://www.mayoclinic.org/diseases-conditions/preeclampsia/symptoms-causes/syc-20355745#:~:text=Preeclampsia%20is%20a%20pregnancy%20complication,blood%20pressure%20had%20been%20normal.
  23. https://www.bornontario.ca/en/index.aspx
  24. https://www.poynter.org/ifcn/

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